The ISNULL function is a built-in SQL function used to replace NULL values with a specified value. It's particularly useful when dealing with data that might contain NULLs, as NULLs can cause problems in calculations and comparisons. For instance, if you're calculating an average, a NULL value will throw off the result. Using ISNULL allows you to substitute the NULL with a meaningful value, like 0 or an empty string, ensuring your calculations and comparisons work as expected. This function is crucial for maintaining data integrity and preventing unexpected errors in your SQL queries. It's important to note that the ISNULL function is not universally supported across all SQL dialects. Some databases use alternative functions like COALESCE, which offers similar functionality but might have slightly different syntax. Understanding the specific function available in your database system is essential for proper implementation.